Natural Antibacterial Protection in Toothpaste with ε-Polylysine
Introduction: Toothpaste is essential for maintaining oral hygiene, but due to its moisture content, it is vulnerable to microbial contamination, especially after the tube is opened. ε-Polylysine, a natural antimicrobial agent, has been proven to inhibit the growth of harmful oral bacteria like Streptococcus mutans and Porphyromonas gingivalis, which are associated with dental cavities and gum disease.
Issues
Microbial Contamination: Toothpaste, especially in moist environments, can easily become contaminated with bacteria and fungi, which could compromise its efficacy and safety.
Shelf Life: Without effective preservatives, toothpaste often has a short shelf life of 6-12 months, particularly when exposed to external factors after opening.
Consumer Demand for Clean-Label Products: Consumers are increasingly looking for natural, chemical-free oral care solutions, making clean-label products with natural preservatives highly desirable.
Solution: ε-Polylysine 0.05%: ε-Polylysine was added to the toothpaste formulation to provide broad-spectrum antibacterial protection. This helps to keep harmful microorganisms like Streptococcus mutans under control, ensuring the toothpaste stays effective and safe throughout its use.
Results
Effective Antibacterial Protection: ε-Polylysine successfully inhibited bacterial growth, particularly Streptococcus mutans and Candida albicans, for up to 12 months without altering the toothpaste’s texture or taste.
Extended Shelf Life: The shelf life of the toothpaste was extended from 6 months to 12 months, providing greater protection against microbial spoilage.
No Sensory Impact: The toothpaste maintained its smooth texture, pleasant minty flavor, and foaming properties, with no significant changes in appearance or performance.
Conclusion: ε-Polylysine provides a highly effective, natural preservative solution in toothpaste, offering antibacterial protection while ensuring extended shelf life and clean-label compliance. This aligns with consumer preferences for safe, natural, and preservative-free oral care products
.jpg)
ε-Polylysine.jpg)
Nisin
Natamycin
Rosemary Extract
