Polylysine Applies in the Pharmaceutical Field
In our preservative application practice, we have accumulated considerable experience in using polylysine in the food field. Thanks to its characteristics of low toxicity and easy metabolism, it has been widely adapted to meet the preservation needs of various foods such as pastries, meat products, and dairy products. It can effectively inhibit common pathogenic bacteria without affecting the flavor of food. However, in the pharmaceutical field, due to the particularity of pharmaceutical systems and compliance requirements, our application experience is still in the exploration stage. Combined with existing practices, the following shares 4 application cases of polylysine in the food field, providing references for the optimization of preservation solutions in related scenarios.
1. Applying in disposable nasal oxygen tubes
During the use of ordinary nasal oxygen tubes, on the one hand, they are prone to bacterial growth, posing an infection risk to patients; on the other hand, the airflow can make patients feel dry in the nasal cavity, affecting usage comfort. After adding polylysine to the water associated with nasal oxygen tubes, relying on the excellent hygroscopic property of polylysine itself, it can effectively alleviate the problem of dry nasal cavity in patients. At the same time, the broad-spectrum antibacterial ability of polylysine can inhibit bacterial growth, fundamentally solving the two major points of ordinary nasal oxygen tubes.
There have been relevant trial feedbacks from some medical institutions now.
2. Combining with medicinal powders for skin surface wound healing
After a skin surface wound occurs, bacterial infection is an important factor affecting the healing speed. Traditional medicinal powders have a certain anti-inflammatory effect, but their antibacterial range and durability are relatively limited. When polylysine is compounded with such medicinal powders, it can give full play to its broad-spectrum antibacterial properties, forming a mild antibacterial protective film on the wound surface. It continuously inhibits the growth of common pathogenic bacteria such as Escherichia coli and Staphylococcus aureus, creating a clean and safe environment for wound healing. This significantly accelerates the wound healing process and reduces the possibility of scar formation.
At present, this direction has achieved good results in the laboratory small-scale test stage.
3. Applying in sutures for artificial meninges
For patients who need craniotomy, artificial meninges are used in some cases to repair defects on the surface of brain tissue, and the absorption effect of sutures directly affects the postoperative recovery. After coating polylysine on the sutures of artificial meninges, it can have good biocompatibility with human tissues, promote the degradation and absorption rate of sutures in the body, reduce the stimulation of foreign body residues to the body, lower the probability of postoperative inflammatory reactions, and help patients recover neurological functions more quickly.
Currently, this technology has launched preliminary cooperation and exploration with relevant medical device R&D enterprises.
4. Applying in sprays for treating skin tinea and beriberi
Skin tinea and beriberi are mainly caused by fungal and bacterial infections. Although traditional sprays can temporarily relieve symptoms, recurrence is likely. Relying on its broad-spectrum antibacterial property that can inhibit both fungi and bacteria, after polylysine is added to such sprays, it can more thoroughly eliminate pathogenic bacteria on the skin surface. At the same time, it forms a long-acting antibacterial layer on the skin surface, effectively preventing recurrence. Moreover, polylysine itself has good safety, no irritation to the skin, and is suitable for long-term use.
Some daily chemical enterprises have introduced polylysine ingredients in the R&D of such products up to now.
We look forward to working with you to expand new horizons for polylysine. Please bring your questions—Bainafo is here waiting for you.
